| Friday, September 17, 2010 | ||||
| Player | From | To | Fee | |
| Frank Nouble | West Ham United | Swansea City | Loan | |
| Luke Daniels | West Bromwich Albion | Charlton Athletic | Loan | |
| Peter Gulacsi | Liverpool | Tranmere Rovers | Loan | |
| Thursday, September 16, 2010 | ||||
| Player | From | To | Fee | |
| Oliver Norwood | Manchester United | Carlisle United | Loan | |
| Monday, September 13, 2010 | ||||
| Player | From | To | Fee | |
| Kyle Walker | Tottenham Hotspur | Queens Park Rangers | Loan | |
| Saturday, September 11, 2010 | ||||
| Player | From | To | Fee | |
| Daniel Ayala | Liverpool | Hull City | Loan | |
| Jason Brown | Blackburn Rovers | Leeds United | Loan | |
| Liam Lawrence | Stoke City | Portsmouth | Loan | |
| Friday, September 10, 2010 | ||||
| Player | From | To | Fee | |
| Daniel Ward | Bolton Wanderers | Coventry City | Loan | |
| Garry O'Connor | Birmingham | Barnsley | Loan | |
| Thursday, September 9, 2010 | ||||
| Player | From | To | Fee | |
| Danny Rose | Tottenham Hotspur | Bristol City | Loan | |
| David Davis | Wolverhampton Wanderers | Walsall | Loan | |
| Jake Kean | Blackburn Rovers | Hartlepool United | Loan | |
| Wednesday, September 8, 2010 | ||||
| Player | From | To | Fee | |
| James Vaughan | Everton | Crystal Palace | Loan | |
| Friday, September 3, 2010 | ||||
| Player | From | To | Fee | |
| Andy Marshall | Unattached | Aston Villa | Free | |
| Wednesday, September 1, 2010 | ||||
| Player | From | To | Fee | |
| David Carney | Twente Enschede | Blackpool | Undisclosed | |
| Joseph Yobo | Everton | Fenerbahce | Loan | |
| Monday, August 30, 2010 | ||||
| Player | From | To | Fee | |
| Fabio Daprela | West Ham United | Brescia | Undisclosed | |
| Javier Mascherano | Liverpool | Barcelona | Undisclosed | |
| Paul Scharner | Unattached | West Bromwich Albion | Free | |
| Harry Forrester | Aston Villa | Kilmarnock | Loan | |
| Saturday, August 28, 2010 | ||||
| Player | From | To | Fee | |
| Raul Meireles | FC Porto | Liverpool | £11,500,000 | |
| Hatem Ben Arfa | Marseille | Newcastle United | Loan | |
| Friday, August 27, 2010 | ||||
| Player | From | To | Fee | |
| Carlos Salcido | PSV Eindhoven | Fulham | Undisclosed | Story |
| Ismael Tioté | Twente Enschede | Newcastle United | Undisclosed | |
| Marc-Antoine Fortune | Celtic | West Bromwich Albion | Undisclosed | |
| Benjani Mwaruwari | Unattached | Blackburn Rovers | Free | Story |
| Luke Varney | Derby County | Blackpool | Loan | |
| Victor Obinna | Internazionale | West Ham United | Loan | |
| Thursday, August 26, 2010 | ||||
| Player | From | To | Fee | |
| Sebastien Squillaci | Sevilla FC | Arsenal | Undisclosed | |
| Harry Forrester | Aston Villa | Kilmarnock | Loan | |
| Leon Barnett | West Bromwich Albion | Norwich City | Loan | |
| Leon Barnett | West Bromwich Albion | Norwich City | Loan | |
| Michael Mancienne | Chelsea | Wolverhampton Wanderers | Loan | |
| Wednesday, August 25, 2010 | ||||
| Player | From | To | Fee | |
| Kristian Nemeth | Liverpool | Olympiakos | Undisclosed | |
| Alberto Aquilani | Liverpool | Juventus | Loan | Story |
| Andrew Keogh | Wolverhampton Wanderers | Cardiff City | Loan | Story |
| Tuesday, August 24, 2010 | ||||
| Player | From | To | Fee | |
| Alessandro Diamanti | West Ham United | Brescia | £1,800,000 | |
| Rafik Halliche | Benfica | Fulham | Undisclosed | Story |
| Fraser Forster | Newcastle United | Celtic | Loan | |
| Nemanja Matic | Chelsea | Vitesse Arnhem | Loan | |
| Slobodan Rajkovic | Chelsea | Vitesse Arnhem | Loan | |
| Monday, August 23, 2010 | ||||
| Player | From | To | Fee | |
| Diego | Liverpool | Cesena | Undisclosed | |
| Jason Scotland | Wigan Athletic | Ipswich Town | Undisclosed | |
| Steven Caldwell | Unattached | Wigan Athletic | Free | |
| Sunday, August 22, 2010 | ||||
| Player | From | To | Fee | |
| William Gallas | Unattached | Tottenham Hotspur | Free | |
| Saturday, August 21, 2010 | ||||
| Player | From | To | Fee | |
| Alex Marrow | Blackburn Rovers | Crystal Palace | Loan | |
| Friday, August 20, 2010 | ||||
| Player | From | To | Fee | |
| Peter Odemwingie | Lokomotiv Moscow | West Bromwich Albion | Undisclosed | |
| Somen Tchoyi | SV Salzburg | West Bromwich Albion | Undisclosed | |
| Jonathan Obika | Tottenham Hotspur | Crystal Palace | Loan | |
| Luke Hubbins | Birmingham | Notts County | Loan | |
| Thursday, August 19, 2010 | ||||
| Player | From | To | Fee | |
| Jay Simpson | Arsenal | Hull City | Undisclosed | |
| Matthew Kilgallon | Sunderland | Middlesbrough | Loan | |
| Reuben Reid | West Bromwich Albion | Walsall | Loan | |
| Vladimir Weiss | Manchester City | Rangers | Loan | Story |
| Wednesday, August 18, 2010 | ||||
| Player | From | To | Fee | |
| Jonathan Walters | Ipswich Town | Stoke City | £2,750,000 | Story |
| Brad Jones | Middlesbrough | Liverpool | £2,300,000 | Story |
| Dorian Dervite | Tottenham Hotspur | Villarreal | Undisclosed | |
| James Milner | Aston Villa | Manchester City | Undisclosed | Story |
| Moussa Dembele | AZ Alkmaar | Fulham | Undisclosed | Story |
| Stephen Ireland | Manchester City | Aston Villa | Undisclosed | Story |
| Dekel Keinan | Unattached | Blackpool | Free | Story |
| Tuesday, August 17, 2010 | ||||
| Player | From | To | Fee | |
| Jake Cassidy | Airbus UK Broughton | Wolverhampton Wanderers | Undisclosed | |
| Craig Bellamy | Manchester City | Cardiff City | Loan | |
| Monday, August 16, 2010 | ||||
| Player | From | To | Fee | |
| Bebé | Guimaraes | Manchester United | Undisclosed | |
| Matt Derbyshire | Olympiakos | Birmingham | Loan | |
| Saturday, August 14, 2010 | ||||
| Player | From | To | Fee | |
| Iain Turner | Everton | Coventry City | Loan | |
| Friday, August 13, 2010 | ||||
| Player | From | To | Fee | |
| Chris Basham | Bolton Wanderers | Blackpool | Undisclosed | |
| James Beattie | Stoke City | Rangers | Undisclosed | |
| Mario Balotelli | Internazionale | Manchester City | Undisclosed | |
| Ramires | Benfica | Chelsea | Undisclosed | |
| Carl Dickinson | Stoke City | Portsmouth | Loan | |
| Ryan Glen Mason | Tottenham Hotspur | Doncaster Rovers | Loan | |
| Thursday, August 12, 2010 | ||||
| Player | From | To | Fee | |
| Christian Poulsen | Juventus | Liverpool | £4,500,000 | Story |
| Ricardo Carvalho | Chelsea | Real Madrid | Undisclosed | Story |
| Tom Eaves | Oldham Athletic | Bolton Wanderers | Undisclosed | |
| Andros Townsend | Tottenham Hotspur | Ipswich Town | Loan | |
| Danny Welbeck | Manchester United | Sunderland | Loan | |
| Dean Parrett | Tottenham Hotspur | Plymouth Argyle | Loan | |
| Jack Cork | Chelsea | Burnley | Loan | |
| Jonathon Routledge | Wigan Athletic | Hamilton Academical | Loan | |
| Kayleden Brown | West Bromwich Albion | Tranmere Rovers | Loan | |
| Wednesday, August 11, 2010 | ||||
| Player | From | To | Fee | |
| Kenwyne Jones | Sunderland | Stoke City | £8,000,000 | |
| Craig Cathcart | Manchester United | Blackpool | Undisclosed | |
| Eliot Grandin | CSKA Sofia | Blackpool | Undisclosed | |
| Ludovic Sylvestre | Mlada Boleslav | Blackpool | Undisclosed | |
| Malaury Martin | AS Monaco | Blackpool | Free | |
| John Mensah | Lyon | Sunderland | Loan | |
| Nedum Onuoha | Manchester City | Sunderland | Loan | |
| Tuesday, August 10, 2010 | ||||
| Player | From | To | Fee | |
| Colin Doyle | Birmingham | Coventry City | Loan | |
| Kyle Bartley | Arsenal | Sheffield United | Loan | |
| Monday, August 9, 2010 | ||||
| Player | From | To | Fee | |
| Scott Sinclair | Chelsea | Swansea City | £500,000 | |
| Nicky Shorey | Aston Villa | West Bromwich Albion | Undisclosed | |
| Andrew Tutte | Manchester City | Rochdale | Loan | |
| Sunday, August 8, 2010 | ||||
| Player | From | To | Fee | |
| Philipp Degen | Liverpool | VfB Stuttgart | Loan | |
| Saturday, August 7, 2010 | ||||
| Player | From | To | Fee | |
| Deco | Chelsea | Fluminense FC | Undisclosed | |
| Joshua King | Manchester United | Preston North End | Loan | |
| Robin Shroot | Birmingham | Cheltenham Town | Loan | |
| Thursday, August 5, 2010 | ||||
| Player | From | To | Fee | |
| Adel Taarabt | Tottenham Hotspur | Queens Park Rangers | Undisclosed | |
| Marton Fulop | Sunderland | Ipswich Town | Undisclosed | Story |
| Winston Reid | FC Midtjylland | West Ham United | Undisclosed | Story |
| Ben Gordon | Chelsea | Kilmarnock | Loan | |
| Jean Yves Mvoto Owono | Sunderland | Oldham Athletic | Loan | |
| Matthew Fry | West Ham United | Charlton Athletic | Loan | |
| Michael Liddle | Sunderland | Leyton Orient | Loan | |
| Oscar Jansson | Tottenham Hotspur | Northampton Town | Loan | |
| Oumare Tounkare | Sunderland | Oldham Athletic | Loan | |
| Ryan Bertrand | Chelsea | Nottingham Forest | Loan | |
| Sam Vokes | Wolverhampton Wanderers | Bristol City | Loan | |
| Wednesday, August 4, 2010 | ||||
| Player | From | To | Fee | |
| Ivan Klasnic | Unattached | Bolton Wanderers | Free | |
| Tuesday, August 3, 2010 | ||||
| Player | From | To | Fee | |
| David Button | Tottenham Hotspur | Plymouth Argyle | Loan | |
| Sanchez Watt | Arsenal | Leeds United | Loan | |
| Tal Ben-Haim | Portsmouth | West Ham United | Loan | |
| Monday, August 2, 2010 | ||||
| Player | From | To | Fee | |
| Danny Philliskirk | Chelsea | Oxford United | Loan | |
| Stefan Maierhofer | Wolverhampton Wanderers | MSV Duisburg | Loan | |
